Bioanalytical Methods

Bioanalytical Method Capabilities

HPLC Analysis

Industry Standard Approach

High-Performance Liquid Chromatography (HPLC) is one of the most widely used techniques for testing from early stage development to final product characterization and QC release testing. Our team offers extensive experience in HPLC methods development, qualification, and validation.

High Level of Expertise

Scorpius offers state-of-the-art HPLC method development, method transfer and method validation for large and small molecule analysis. Our bioanalytical laboratory scientists offer a high level of expertise in developing accurate and robust methods for biological samples analysis, including blood, plasma, serum, and protein-based therapeutics.

Biacore^™ Biomolecules Interaction Analysis

Precise SPR System

The Biacore^™ T200, is a versatile and precise surface plasmon resonance (SPR) system that enables analysis of a wide range of molecular interactions. Enabling label-free interaction analysis, the Biacore platform delivers data on biomolecular interactions. It also offers highly specific analysis, robust data, and efficient time to results for immunogenicity studies at any phase of development.

Range of Molecular Interaction Data:

Kinetics/affinity characterization
Kinetics/affinity screening
Single-cycle kinetics
Low molecular weight interaction analysis
Fragment screening
Epitope mapping
Immunogenicity
Concentration analysis
Calibration-free concentration analysis
Thermodynamics
Comparability

Fluorescent Microscopy

Gentle on Samples

A highly sensitive, specific, and reliable technology for the localization of biomolecules and cells, fluorescence imaging is reasonably gentle on the sample, which facilitates the visualization of molecules and dynamic processes in live cells.

Scorpius has extensive knowledge and expertise in fluorescence microscopy techniques. Fluorescence microscopy allows for investigation of cell surface expression and intracellular localization of proteins. Co-localization of proteins in the intracellular compartment can also be evaluated at high resolution.

Higher Image Quality & Ergonomics

Additionally, cells expressing reporter genes, like GFP, can also be monitored in many situations, including transfection of desired genes. With improved image quality and ergonomics, our Olympus CKX53 inverted microscope delivers stable performance and a comfortable workflow for a variety of cell culture needs, including live cell observation, cell sampling and handling, image capture, and fluorescence observation.

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